Description

2-Amino-3-Chloro-5-Fluoropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen and amine functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogenated pyridine core provides bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: Utilized in exploratory chemistry for constructing heterocyclic libraries and studying structure-activity relationships (SAR).

Basic Information

Product Name	2-Amino-3-Chloro-5-Fluoropyridine
CAS No.	1214330-79-6
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	3-Chloro-5-fluoro-2-pyridinamine; 3-Chloro-5-fluoropyridin-2-amine; 2-Amino-3-chloro-5-fluoropyridine; 5-Fluoro-3-chloro-2-aminopyridine; 3-Chloro-5-fluoro-2-aminopyridine; 2-Pyridinamine, 3-chloro-5-fluoro-; 1214330-79-6
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.