Description

Methyl 3-Bromo-2-Fluoroisonicotinate CAS NO 1214325-32-2 is a high-purity, multi-functional pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical and agrochemical research, enabling the introduction of both bromo and fluoro substituents in a single, reactive ester intermediate. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new herbicides and fungicides where the halogenated pyridine core is essential for bioactivity.
• Material Science: Building block for creating specialized ligands, catalysts, and functional organic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fluorination Chemistry Studies: Serves as a model compound for studying the influence of fluorine atoms on the reactivity and physicochemical properties of heteroaromatic systems.

Basic Information

Product Name	Methyl 3-Bromo-2-Fluoroisonicotinate
CAS No.	1214325-32-2
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	3-Bromo-2-fluoropyridine-4-carboxylic acid methyl ester; Methyl 3-bromo-2-fluoro-4-pyridinecarboxylate; 3-Bromo-2-fluoroisonicotinic acid methyl ester; 2-Fluoro-3-bromoisonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 3-bromo-2-fluoro-, methyl ester; Methyl 3-bromo-2-fluoropyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-2-Fluoroisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.