Description

4-Benzyl-1-(tert-Butoxycarbonyl)Piperazine-2-Carboxylic Acid is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the controlled construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in peptide mimetic design, medicinal chemistry, and the synthesis of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for protease inhibitors and other therapeutic agents.
• Peptide & Peptidomimetic Synthesis: Used to introduce a protected piperazine-2-carboxylic acid moiety into peptide chains, enabling the creation of molecules with enhanced stability and biological activity.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) explorations to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Chemical Biology Research: Serves as a versatile scaffold for developing molecular probes and tools to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, high-value molecules for clients.

Basic Information

Product Name	4-Benzyl-1-(tert-Butoxycarbonyl)Piperazine-2-Carboxylic Acid
CAS No.	1214057-04-1
Molecular Formula	C17H24N2O4
Molecular Weight	320.39 g/mol
Synonyms	1-Boc-4-benzylpiperazine-2-carboxylic acid; tert-Butyl 4-benzyl-2-carboxypiperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-benzylpiperazine-2-carboxylic acid; 4-Benzyl-1-Boc-piperazine-2-carboxylic acid; Boc-4-Bn-Pip(2)-OH; (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-4-benzylpiperazine-2-carboxylic acid (for stereoisomer); 1-N-Boc-4-benzylpiperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Benzyl-1-(tert-Butoxycarbonyl)Piperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.