Description

1-Hexacosanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid derivative, specifically a lysophosphatidylcholine (LPC) with a very long-chain fatty acid. This compound matters for its role as a critical biochemical tool and a potential functional excipient in advanced drug delivery systems, particularly for modulating membrane fluidity and cellular interactions. It is primarily needed by researchers in lipidomics, pharmaceutical developers working on liposomal and nanoparticle formulations, and manufacturers of high-end diagnostic reagents.

Application

• Biochemical Research & Lipidomics: Used as a standard or probe in mass spectrometry-based lipid analysis to study membrane composition, lipid metabolism, and signaling pathways.
• Pharmaceutical Development: Serves as a key component or stabilizer in the formulation of liposomes, niosomes, and other lipid nanoparticles for targeted drug and gene delivery.
• Cell Culture & Membrane Studies: Employed to modify cell membrane properties, study lipid rafts, and investigate the role of specific lysophospholipids in cellular processes.
• Diagnostic Reagents: Utilized in the production of calibrants and controls for clinical diagnostic assays that measure phospholipid levels or related enzymes.
• Cosmetic & Dermal Formulations: Incorporated into high-performance skincare products for its potential emollient and skin-barrier enhancing properties.

Basic Information

Product Name	1-Hexacosanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine
CAS No.	1213783-80-2
Molecular Formula	C34H70NO8P
Molecular Weight	651.89 g/mol
Synonyms	LysoPC(26:0); 1-Cerotoyl-2-hydroxy-sn-glycero-3-phosphocholine; LPC(26:0); Lysophosphatidylcholine(26:0); Hexacosanoyl lysophosphatidylcholine; 2-Hydroxy-1-hexacosanoyl-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine, 1-hexacosanoyl-2-hydroxy-; (2R)-2-Hydroxy-3-(trimethylazaniumyl)propyl hexacosanoate hydrogen phosphate
EINECS	Contact for details

Quality Control

Our 1-Hexacosanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR & MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.