Description

(3S)-3-(4-Bromophenyl)Morpholine is a chiral morpholine derivative featuring a brominated aromatic ring, serving as a high-value synthetic building block. This compound is critical for pharmaceutical research and development, particularly in the creation of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of central nervous system (CNS) drugs, kinase inhibitors, and other therapeutic agents.
• Asymmetric Catalysis: Used as a ligand precursor or a chiral auxiliary in transition metal-catalyzed reactions to induce stereoselectivity.
• Agrochemical Research: Building block for novel, enantiopure herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer or functional additive in the synthesis of specialty polymers with tailored optical or electronic properties.
• Chemical Biology: Probe molecule for studying enzyme-substrate interactions and biological pathways.
• Process Chemistry: Scalable intermediate for the commercial manufacturing of chiral drugs under Good Manufacturing Practice (GMP) standards.

Basic Information

Product Name	(3S)-3-(4-Bromophenyl)Morpholine
CAS No.	1213365-04-8
Molecular Formula	C10H12BrNO
Molecular Weight	242.11 g/mol
Synonyms	(S)-3-(4-Bromophenyl)morpholine; (3S)-3-(p-Bromophenyl)morpholine; 4-Bromo-α-[(S)-morpholin-3-yl]benzene; 4-Bromo-α-[(3S)-morpholin-3-yl]benzene; (S)-3-(4-Bromophenyl)tetrahydro-1,4-oxazine; (3S)-3-(4-Bromophenyl)-1,4-oxazinane; 1213365-04-8; (S)-3-(4-Bromophenyl)morpholine
EINECS	Contact for details

Quality Control

Every batch of (3S)-3-(4-Bromophenyl)Morpholine is produced and tested under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with industry standards for research and development. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.