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(2S)-2-Amino-2-(6-Bromo(3-Pyridyl))Ethan-1-Ol CAS NO 1213204-08-0


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CAS No.:1213204-08-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S)-2-Amino-2-(6-Bromo(3-Pyridyl))Ethan-1-Ol is a high-purity chiral building block featuring a brominated pyridine core and an amino alcohol functional group. This compound is critical for pharmaceutical research and development, serving as a key intermediate in the synthesis of complex, biologically active molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel drug candidates and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.
  • Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce specific stereochemistry and functional groups.
  • Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents and herbicides.
  • Ligand and Catalyst Development: The amino alcohol moiety can be utilized in the preparation of chiral ligands for asymmetric catalysis.
  • Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
  • Process Chemistry: Used in scale-up and route development for the commercial manufacturing of fine chemicals.

Basic Information

Product Name (2S)-2-Amino-2-(6-Bromo(3-Pyridyl))Ethan-1-Ol
CAS No. 1213204-08-0
Molecular Formula C7H9BrN2O
Molecular Weight 217.07 g/mol
Synonyms (2S)-2-Amino-2-(6-bromopyridin-3-yl)ethanol; 6-Bromo-3-pyridinemethanol, α-amino-, (αS)-; (S)-2-Amino-2-(6-bromo-3-pyridinyl)ethanol; (S)-2-Amino-2-(6-bromopyridin-3-yl)ethan-1-ol; 2-Amino-2-(6-bromo-3-pyridyl)ethanol (S-enantiomer); (S)-6-Bromo-3-(2-amino-2-hydroxyethyl)pyridine; (S)-2-(6-Bromopyridin-3-yl)-2-aminoethanol
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Quality Control

Our (2S)-2-Amino-2-(6-Bromo(3-Pyridyl))Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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