Description

(R)-2-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)Piperazine is a chiral piperazine derivative featuring a benzodioxane moiety, serving as a crucial building block in advanced organic synthesis. This compound is valued for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel compounds with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel central nervous system (CNS) agents, receptor modulators, and other therapeutic candidates.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals for material science and electronics applications.
• Academic and R&D: A valuable compound for medicinal chemistry research, process development, and exploring new synthetic methodologies in university and industrial labs.

Basic Information

Product Name	(R)-2-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)Piperazine
CAS No.	1213024-25-9
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	(R)-6-(Piperazin-2-yl)-2,3-dihydro-1,4-benzodioxine; (R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)piperazine; (R)-2-(1,4-Benzodioxan-6-yl)piperazine; (R)-2-(Benzo[1,4]dioxin-6-yl)piperazine; (R)-Benzodioxanylpiperazine; (R)-6-(2-Piperazinyl)-1,4-benzodioxane; (R)-enantiomer of 1213024-25-9
EINECS	Contact for details

Quality Control

Our (R)-2-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.