Description

(R)-2-(Trifluoromethyl)Piperidine is a high-value, chiral piperidine derivative distinguished by the presence of a trifluoromethyl group. This compound is a critical building block in modern pharmaceutical and agrochemical research, where its unique stereochemistry and fluorine atoms are leveraged to modulate the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the CF3 group enhances compound efficacy and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for specialty polymers with unique surface properties.
• Fluorine Chemistry Studies: A valuable reference compound for studying the stereoelectronic effects of the trifluoromethyl group in heterocyclic systems.

Basic Information

Product Name	(R)-2-(Trifluoromethyl)Piperidine
CAS No.	1212734-83-2
Molecular Formula	C6H10F3N
Molecular Weight	153.15 g/mol
Synonyms	(R)-2-(Trifluoromethyl)piperidine; (R)-α-(Trifluoromethyl)piperidine; (R)-Piperidine-2-trifluoromethyl; (2R)-2-(Trifluoromethyl)piperidine; (+)-2-(Trifluoromethyl)piperidine; (R)-2-Trifluoromethylpiperidine; 2-(Trifluoromethyl)piperidine, (R)-; 1212734-83-2
EINECS	Contact for details

Quality Control

Our (R)-2-(Trifluoromethyl)Piperidine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.