Description

(4Ar,7As)-1-(3-Methoxyphenyl)-4-(3-Methylbutyl)Hexahydrothieno[3,4-B]Pyrazin-2(1H)-One 6,6-Dioxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure containing a sulfone group. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents, particularly within central nervous system (CNS) and other specialized drug discovery programs. It is primarily targeted at pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Development: Serves as a key chiral intermediate in the production pathway for complex, high-value active pharmaceutical ingredients.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(4Ar,7As)-1-(3-Methoxyphenyl)-4-(3-Methylbutyl)Hexahydrothieno[3,4-B]Pyrazin-2(1H)-One 6,6-Dioxide
CAS No.	1212457-57-2
Molecular Formula	C18H26N2O4S
Molecular Weight	366.48 g/mol
Synonyms	Hexahydrothieno[3,4-b]pyrazin-2(1H)-one, 1-(3-methoxyphenyl)-4-(3-methylbutyl)-, 6,6-dioxide, (4aR,7aS)-; (4aR,7aS)-1-(3-Methoxyphenyl)-4-(3-methylbutyl)hexahydro-1H-thieno[3,4-b]pyrazine-2,6-dione 6,6-dioxide; 1212457-57-2; Thienopyrazine dioxide derivative; Pharmaceutical intermediate 1212457-57-2.
EINECS	Contact for details

Quality Control

Our (4Ar,7As)-1-(3-Methoxyphenyl)-4-(3-Methylbutyl)Hexahydrothieno[3,4-B]Pyrazin-2(1H)-One 6,6-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.