Description

cis-Octahydrothieno[3,4-B]Pyrazine 6,6-Dioxide (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and free base form. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its defined structure is essential for ensuring the efficacy and safety of the final drug product. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries working on novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly those containing fused bicyclic systems.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in developing and optimizing robust, scalable manufacturing routes for clinical and commercial drug supplies.
• Chemical Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	cis-Octahydrothieno[3,4-B]Pyrazine 6,6-Dioxide (Saltdata: Free)
CAS No.	1212331-13-9
Molecular Formula	C6H10N2O2S
Molecular Weight	174.22 g/mol
Synonyms	cis-Octahydrothieno[3,4-b]pyrazine 6,6-dioxide; (3aR,6aR)-Hexahydro-1H-thieno[3,4-b]pyrazine 5,5-dioxide; cis-Hexahydro-1H-thieno[3,4-b]pyrazine 5,5-dioxide; (3aR,6aR)-Octahydrothieno[3,4-b]pyrazine 6,6-dioxide; Thienopyrazine dioxide intermediate; Free base of cis-octahydrothienopyrazine dioxide.
EINECS	Contact for details

Quality Control

Our cis-Octahydrothieno[3,4-B]Pyrazine 6,6-Dioxide (Saltdata: Free) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.