Description

1-(Pyridin-4-Yl)Cyclobutanamine is a specialized organic compound featuring a cyclobutane ring linked to an aminopyridine moiety, making it a valuable nitrogen-containing heterocyclic building block. This structural motif is critical for medicinal chemistry research, particularly in the development of novel small molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Chemical Biology Probe Development: Serves as a core scaffold for creating tool compounds to study biological pathways and target validation.
• Agrochemical Synthesis: Potential intermediate in the development of novel crop protection agents and pesticides.
• Ligand for Catalysis: Can be employed in the design of novel chiral ligands for asymmetric synthesis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(Pyridin-4-Yl)Cyclobutanamine
CAS No.	1211593-50-8
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	4-(1-Aminocyclobutyl)pyridine; 1-(4-Pyridinyl)cyclobutanamine; 1-Pyridin-4-ylcyclobutan-1-amine; Cyclobutanamine, 1-(4-pyridinyl)-; 1-(Pyridin-4-yl)cyclobutan-1-amine
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-4-Yl)Cyclobutanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.