Description

1-Pyridin-2-Yl-Cyclobutanecarbaldehyde is a high-purity, versatile aldehyde building block featuring a cyclobutane ring fused with a pyridine moiety. This unique heterocyclic structure makes it a critical intermediate for the synthesis of complex molecules in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, agrochemicals, and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its rigid, three-dimensional cyclobutane scaffold.
• Agrochemical Synthesis: Intermediate in the development of new active ingredients for crop protection products.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for advanced organic frameworks and functional polymers with specific electronic properties.
• Chemical Biology: Used in the design and synthesis of molecular probes and bio-conjugates for studying biological systems.

Basic Information

Product Name	1-Pyridin-2-Yl-Cyclobutanecarbaldehyde
CAS No.	1211593-36-0
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	2-(1-Formylcyclobutyl)pyridine; 1-(Pyridin-2-yl)cyclobutanecarboxaldehyde; Cyclobutanecarboxaldehyde, 1-(2-pyridinyl)-; 1-(2-Pyridyl)cyclobutanecarbaldehyde; 1-(Pyridin-2-yl)cyclobutanecarbaldehyde; 1-Pyridin-2-ylcyclobutanecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1-Pyridin-2-Yl-Cyclobutanecarbaldehyde is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity research specifications, with comprehensive Certificates of Analysis (COA) provided for each lot, detailing results from HPLC, NMR, and other relevant analytical methods.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.