Description

6-Chloro-3-Fluoro-2-Iodopyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogenated pyridine core contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, enabling challenging cross-coupling and functionalization reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as those used in OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	6-Chloro-3-Fluoro-2-Iodopyridine
CAS No.	1211590-36-1
Molecular Formula	C5H2ClFIN
Molecular Weight	273.43 g/mol
Synonyms	2-Iodo-6-chloro-3-fluoropyridine; 3-Fluoro-6-chloro-2-iodopyridine; 6-Chloro-3-fluoro-2-iodopyridine; Pyridine, 6-chloro-3-fluoro-2-iodo-; 2-Iodo-3-fluoro-6-chloropyridine; 6-Chloro-2-iodo-3-fluoropyridine; 1211590-36-1
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Fluoro-2-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of research and pre-clinical development. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.