Description

3-Fluoro-5-Methoxypyridin-2-Amine is a high-purity, multi-functional pyridine derivative building block essential for modern synthetic chemistry. Its value lies in the strategic combination of fluorine and methoxy substituents, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and bioavailability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers used in advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, fluorinated heterocyclic scaffolds.
• Academic Research: Used in university and institutional labs for methodological development in cross-coupling and amination reactions.

Basic Information

Product Name	3-Fluoro-5-Methoxypyridin-2-Amine
CAS No.	1211589-70-6
Molecular Formula	C6H7FN2O
Molecular Weight	142.13 g/mol
Synonyms	2-Amino-3-fluoro-5-methoxypyridine; 3-Fluoro-5-methoxy-2-pyridinamine; 5-Methoxy-3-fluoropyridin-2-amine; 2-Pyridinamine, 3-fluoro-5-methoxy-; 1211589-70-6; 3-Fluoro-5-methoxypyridin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Methoxypyridin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.