Description

3-Aminomethyl-5-Bromo-2-Fluoropyridine is a high-value, multi-functional heterocyclic building block featuring a reactive aminomethyl group and halogen substituents. This compound matters for its versatility in facilitating complex molecular construction, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific pharmacophores or structural motifs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine core provides bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Functional Material Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring this precise bromo-fluoro-aminomethyl substituted pyridine.

Basic Information

Product Name	3-Aminomethyl-5-Bromo-2-Fluoropyridine
CAS No.	1211584-25-6
Molecular Formula	C6H6BrFN2
Molecular Weight	205.03 g/mol
Synonyms	(5-Bromo-2-fluoropyridin-3-yl)methanamine; 5-Bromo-2-fluoro-3-pyridinemethanamine; 3-(Aminomethyl)-5-bromo-2-fluoropyridine; 2-Fluoro-5-bromo-3-pyridinemethylamine; 5-Bromo-2-fluoro-3-(aminomethyl)pyridine; 3-Pyridinemethanamine, 5-bromo-2-fluoro-; (5-Bromo-2-fluoro-3-pyridinyl)methanamine
EINECS	Contact for details

Quality Control

Our 3-Aminomethyl-5-Bromo-2-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.