Description

2-Methyl-5-(2,2,2-Trifluoroethyl)Nicotinic Acid is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise introduction of the trifluoroethyl group, which is essential for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the trifluoroethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for creating specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Methyl-5-(2,2,2-Trifluoroethyl)Nicotinic Acid
CAS No.	1211584-21-2
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	5-(2,2,2-Trifluoroethyl)-2-methylnicotinic acid; 2-Methyl-5-(2,2,2-trifluoroethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-(2,2,2-trifluoroethyl)-2-methyl-; 1211584-21-2; 2-Methyl-5-trifluoroethylnicotinic acid
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-5-(2,2,2-Trifluoroethyl)Nicotinic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.