Description

3-Bromo-5-Nitropicolinic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromo and nitro substituents on the picolinic acid core, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	3-Bromo-5-Nitropicolinic Acid
CAS No.	1211583-91-3
Molecular Formula	C6H3BrN2O4
Molecular Weight	247.01 g/mol
Synonyms	5-Nitro-3-bromopyridine-2-carboxylic acid; 3-Bromo-5-nitropyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 3-bromo-5-nitro-; Picolinic acid, 3-bromo-5-nitro-; 3-Bromo-5-nitro-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Nitropicolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.