Description

2-Amino-3-Fluoro-4-Formylpyridine is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a formyl group on a fluorinated pyridine ring, makes it an invaluable precursor for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Building block for developing new-generation herbicides, fungicides, and insecticides that leverage fluorine's metabolic stability and lipophilicity.
• Ligand Synthesis: Used to create sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs) due to its nitrogen donor sites and formyl group for further functionalization.
• Material Science: Intermediate in the production of specialty polymers, dyes, and photoactive materials where the fluoropyridine core imparts specific electronic properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and for exploring new reaction pathways involving fluorinated heterocycles.

Basic Information

Product Name	2-Amino-3-Fluoro-4-Formylpyridine
CAS No.	1211582-66-9
Molecular Formula	C6H5FN2O
Molecular Weight	140.11 g/mol
Synonyms	3-Fluoro-4-formylpyridin-2-amine; 4-Formyl-3-fluoro-2-pyridinamine; 2-Pyridinamine, 3-fluoro-4-formyl-; 3-Fluoro-2-amino-4-formylpyridine; 2-Amino-3-fluoro-4-pyridinecarboxaldehyde; 4-Formyl-3-fluoropyridin-2-amine
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Fluoro-4-Formylpyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, prolonged exposure to light, heat, or air should be avoided. For long-term storage, consider keeping the material under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.