Description

Methyl 4-Formylnicotinate CAS NO 1211579-85-9 is a high-purity, versatile nicotinate derivative featuring both an ester and an aldehyde functional group on the pyridine ring. This bifunctional nature makes it a critical advanced pharmaceutical intermediate for synthesizing complex molecules, particularly in medicinal chemistry. It is primarily utilized by research organizations, CROs/CDMOs, and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides due to its reactive aldehyde moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and constructing molecular libraries.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and dyes.

Basic Information

Product Name	Methyl 4-Formylnicotinate
CAS No.	1211579-85-9
Molecular Formula	C8H7NO3
Molecular Weight	165.15 g/mol
Synonyms	4-Formylnicotinic Acid Methyl Ester; Methyl 4-Pyridinecarboxylate-4-carboxaldehyde; 4-Carbomethoxypyridine-4-carboxaldehyde; 4-(Methoxycarbonyl)pyridine-4-carbaldehyde; Nicotinic acid, 4-formyl-, methyl ester; 4-Formylpyridine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Formylnicotinate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality system supports cGMP standards for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.