Description

3-Iodo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused cyclopentane-pyridine ring system with an iodine substituent, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic scaffold.
• Material Science: Acts as a building block for organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to introduce the dihydrocyclopentapyridine moiety into more complex systems.
• Chemical Biology: Utilized as a probe or tag in bioconjugation and labeling studies due to its reactive halogen functionality.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for method development and exploratory synthesis projects.

Basic Information

Product Name	3-Iodo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine
CAS No.	1211578-28-7
Molecular Formula	C8H8IN
Molecular Weight	245.06 g/mol
Synonyms	3-Iodo-6,7-dihydro-5H-cyclopenta[b]pyridine; 6,7-Dihydro-5H-cyclopenta[b]pyridin-3-yl iodide; 3-Iodocyclopenta[b]pyridine; 3-Iodo-5H-cyclopenta[b]pyridine; 3-Iodo-6,7-dihydrocyclopenta[b]pyridine; Cyclopenta[b]pyridine, 3-iodo-6,7-dihydro-5H-
EINECS	Contact for details

Quality Control

Our 3-Iodo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.