Description

tert-Butyl 4-(Piperidin-3-Ylmethyl)Piperazine-1-Carboxylate is a high-value, protected piperazine-piperidine hybrid building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile, nitrogen-rich scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), especially within therapeutic areas targeting the central nervous system, oncology, and infectious diseases.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those requiring complex amine-containing heterocycles.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis or as pharmacophores in receptor-binding studies.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) and CDMOs producing specialized compounds on scale.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	tert-Butyl 4-(Piperidin-3-Ylmethyl)Piperazine-1-Carboxylate
CAS No.	1211569-09-3
Molecular Formula	C16H31N3O2
Molecular Weight	297.44 g/mol
Synonyms	1-Boc-4-(3-piperidinylmethyl)piperazine; tert-Butyl 4-[(piperidin-3-yl)methyl]piperazine-1-carboxylate; 4-(Piperidin-3-ylmethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-piperidinylmethyl)piperazine; 3-[(1-Boc-piperazin-4-yl)methyl]piperidine; BOC-Piperazine-Piperidine Hybrid; 1211569-09-3 (CAS)
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Piperidin-3-Ylmethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.