Description

tert-Butyl (5-Bromo-2-Methylpyridin-3-Yl)Carbamate is a high-purity, synthetically valuable chemical building block. This compound is essential for research and development in advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Material Science: Serves as a precursor for functionalized ligands and monomers used in advanced polymers and coatings.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig aminations.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl (5-Bromo-2-Methylpyridin-3-Yl)Carbamate
CAS No.	1211538-57-6
Molecular Formula	C12H17BrN2O2
Molecular Weight	301.18 g/mol
Synonyms	Boc-5-Bromo-2-methyl-3-aminopyridine; 5-Bromo-2-methylpyridin-3-amine, N-Boc-protected; tert-Butyl N-(5-bromo-2-methyl-3-pyridinyl)carbamate; 3-((tert-Butoxycarbonyl)amino)-5-bromo-2-methylpyridine; 5-Bromo-2-methyl-3-((tert-butoxycarbonyl)amino)pyridine; 1211538-57-6; Boc-3-Amino-5-bromo-2-methylpyridine; N-Boc-5-bromo-2-methylpyridin-3-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Bromo-2-Methylpyridin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We can support development projects with material produced under GMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.