Description

5-Cyclopropylpyrazine-2-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrazine core imparts specific biological and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Advanced Material Research: A starting material for the synthesis of functionalized heterocycles used in organic electronics and polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	5-Cyclopropylpyrazine-2-Carboxylic Acid
CAS No.	1211537-40-4
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	5-Cyclopropyl-2-pyrazinecarboxylic acid; Cyclopropylpyrazinecarboxylic acid; 2-Pyrazinecarboxylic acid, 5-cyclopropyl-; 5-Cyclopropylpyrazine-2-carboxylic acid; 1211537-40-4; 5-Cyclopropyl-2-carboxypyrazine; 5-Cyclopropylpyrazinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Cyclopropylpyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation (IR, NMR), and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.