Description

5-Chloro-2-Fluoro-4-Methoxypyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology: Employed as a molecular probe or a building block for bioconjugation in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methoxypyridine
CAS No.	1211537-31-3
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	2-Fluoro-5-chloro-4-methoxypyridine; 4-Methoxy-5-chloro-2-fluoropyridine; 5-Chloro-2-fluoro-4-methoxypyridine; 2-Fluoro-4-methoxy-5-chloropyridine; Pyridine, 5-chloro-2-fluoro-4-methoxy-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Methoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.