Description

3-Chloro-5-Hydroxypyridine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a carboxylic acid group with chloro and hydroxy substituents on the pyridine ring, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional organic materials and metal-organic frameworks (MOFs).
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis projects.

Basic Information

Product Name	3-Chloro-5-Hydroxypyridine-2-Carboxylic Acid
CAS No.	1211536-84-3
Molecular Formula	C6H4ClNO3
Molecular Weight	173.55 g/mol
Synonyms	2-Carboxy-3-chloro-5-hydroxypyridine; 3-Chloro-5-hydroxypicolinic Acid; 5-Hydroxy-3-chloropicolinic Acid; 3-Chloro-5-hydroxypyridine-2-carboxylic acid; 3-Chloro-5-hydroxy-2-pyridinecarboxylic acid; 3-Chloro-5-hydroxypyridine-2-carboxylate; 3-Chloro-5-hydroxypicolinate
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Hydroxypyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its acidic nature, ensure containers are properly sealed and handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.