Description

3-Chloro-2-(Trifluoromethyl)Isonicotinaldehyde is a high-value, multi-functional chemical building block characterized by its unique halogenated and trifluoromethylated pyridine core. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Ligand and Catalyst Development: Serves as a versatile building block for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-withdrawing groups and rigid structure.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Chloro-2-(Trifluoromethyl)Isonicotinaldehyde
CAS No.	1211536-77-4
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	3-Chloro-2-(trifluoromethyl)pyridine-4-carbaldehyde; 4-Pyridinecarboxaldehyde, 3-chloro-2-(trifluoromethyl)-; 3-Chloro-2-trifluoromethylisonicotinaldehyde; 3-Chloro-2-(trifluoromethyl)-4-pyridinecarboxaldehyde; 3-Chloro-2-(trifluoromethyl)isonicotinaldehyde; 3-Chloro-2-(trifluoromethyl)-4-formylpyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(Trifluoromethyl)Isonicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.