Description

3-Hydroxy-2-Bromo-6-Trifluoromethylpyridine is a high-value, multi-functional heterocyclic building block characterized by its bromo and trifluoromethyl substituents. This compound is essential for medicinal chemistry and agrochemical research, where its unique structure enables the synthesis of novel active ingredients with enhanced properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its halogen and electron-withdrawing groups.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	3-Hydroxy-2-Bromo-6-Trifluoromethylpyridine
CAS No.	1211526-50-9
Molecular Formula	C6H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	2-Bromo-3-hydroxy-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-pyridinol, 2-bromo- derivative; 2-Bromo-6-(trifluoromethyl)pyridin-3-ol; 3-Pyridinol, 2-bromo-6-(trifluoromethyl)-; 2-Bromo-3-hydroxy-6-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-2-Bromo-6-Trifluoromethylpyridine adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.