Description

5-(Chloromethyl)-2-Pyrazinecarbonitrile is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is particularly significant for its bifunctional reactivity, featuring both a chloromethyl group and a nitrile moiety on a pyrazine core, enabling diverse derivatization pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to develop advanced fungicides and herbicides with novel modes of action.
• Ligand and Chelator Development: Serves as a starting material for creating specialized pyrazine-based ligands for catalysis and metal complexation.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis Building Block: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	5-(Chloromethyl)-2-Pyrazinecarbonitrile
CAS No.	1211526-07-6
Molecular Formula	C7H4ClN3
Molecular Weight	165.58 g/mol
Synonyms	2-Pyrazinecarbonitrile, 5-(chloromethyl)-; 5-(Chloromethyl)pyrazine-2-carbonitrile; 2-Cyano-5-(chloromethyl)pyrazine; (Chloromethyl)pyrazinecarbonitrile; 5-Chloromethyl-2-cyanopyrazine; Pyrazine-2-carbonitrile, 5-(chloromethyl)-; 1211526-07-6
EINECS	Contact for details

Quality Control

Every batch of 5-(Chloromethyl)-2-Pyrazinecarbonitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.