Description

2-Bromo-3-Chloropyridin-4-Ol is a halogenated pyridine derivative serving as a versatile and high-value synthetic intermediate. Its unique substitution pattern makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily utilized by pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Useful for designing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	2-Bromo-3-Chloropyridin-4-Ol
CAS No.	1211525-75-5
Molecular Formula	C5H3BrClNO
Molecular Weight	208.44 g/mol
Synonyms	4-Hydroxy-2-bromo-3-chloropyridine; 2-Bromo-3-chloro-4-hydroxypyridine; 3-Chloro-2-bromopyridin-4-ol; 2-Bromo-3-chloro-4-pyridinol; 4-Pyridinol, 2-bromo-3-chloro-; 3-Chloro-2-bromo-4-hydroxypyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Chloropyridin-4-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.