Description

4-Chloro-6-Fluoronicotinic Acid is a high-value halogenated nicotinic acid derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both chloro and fluoro substituents on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen atoms enhance biological activity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional organic materials, such as liquid crystals and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-6-Fluoronicotinic Acid
CAS No.	1211525-00-6
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.55 g/mol
Synonyms	6-Fluoro-4-chloropyridine-3-carboxylic acid; 4-Chloro-6-fluoropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-chloro-6-fluoro-; 4-Chloro-6-fluoro-3-pyridinecarboxylic acid; 1211525-00-6; 4-Chloro-6-fluoronicotinate
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoronicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.