Description

3-(tert-Butyl)-8-Chloro-1-Iodoimidazo[1,5-A]Pyrazine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique halogenated structure, which provides distinct reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, drug discovery, and material science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the discovery and development of new crop protection agents, leveraging its halogenated imidazopyrazine core.
• Material Science: Serves as a precursor for the creation of specialized organic electronic materials and ligands for catalytic systems.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization due to its reactive iodine and chlorine sites for further functionalization.
• Chemical Biology: Employed as a probe or tag in biochemical research, utilizing the iodine atom for potential radiolabeling or cross-coupling reactions.
• Custom Synthesis: A versatile starting material for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	3-(tert-Butyl)-8-Chloro-1-Iodoimidazo[1,5-A]Pyrazine
CAS No.	1211524-21-8
Molecular Formula	C10H11ClIN3
Molecular Weight	335.57 g/mol
Synonyms	8-Chloro-3-tert-butyl-1-iodoimidazo[1,5-a]pyrazine; 1-Iodo-8-chloro-3-(tert-butyl)imidazo[1,5-a]pyrazine; 3-tert-Butyl-8-chloro-1-iodoimidazo[1,5-a]pyrazine; Imidazo[1,5-a]pyrazine, 8-chloro-3-(1,1-dimethylethyl)-1-iodo-; 8-Chloro-3-(tert-butyl)-1-iodoimidazo[1,5-a]pyrazine; 1211524-21-8; tert-Butyl Chloro Iodo Imidazopyrazine
EINECS	Contact for details

Quality Control

Our 3-(tert-Butyl)-8-Chloro-1-Iodoimidazo[1,5-A]Pyrazine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems support development and cGMP manufacturing needs for the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.