Description

4-Chloro-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is a high-value heterocyclic building block and key synthetic intermediate. This compound is essential for medicinal chemistry research and the development of novel pharmaceutical agents, particularly kinase inhibitors. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Core scaffold in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: A versatile building block for constructing fused heterocyclic libraries in drug discovery programs.
• Biochemical Research: Used as a precursor for developing enzyme probes and molecular tools.
• Agrochemical Development: Intermediate in the research and synthesis of novel crop protection agents.
• Chemical Synthesis: Serves as a key starting material for further functionalization to create diverse chemical entities.

Basic Information

Product Name	4-Chloro-1H-Pyrazolo[3,4-B]Pyridin-3-Amine
CAS No.	1211520-57-8
Molecular Formula	C6H5ClN4
Molecular Weight	168.58 g/mol
Synonyms	4-Chloro-1H-pyrazolo[3,4-b]pyridin-3-amine; 3-Amino-4-chloro-1H-pyrazolo[3,4-b]pyridine; 4-Chloro-3-amino-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridin-3-amine, 4-chloro-; 1211520-57-8; 4-Chloro-1H-pyrazolo[3,4-b]pyridin-3-ylamine; 4-Chloro-3-pyrazolopyridinamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.