Description

Methyl 6-Chloro-5-(Trifluoromethyl)Picolinate is a high-value, multi-functional chemical intermediate characterized by its picolinate core and halogenated trifluoromethyl substituent. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where its unique structure imparts critical biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development teams in the crop protection and fine chemical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key building block in the synthesis of next-generation herbicides and fungicides, particularly those targeting broadleaf weeds and resistant fungal strains.
• Pharmaceutical Synthesis: Serves as a versatile precursor for developing active pharmaceutical ingredients (APIs) with improved potency and pharmacokinetic profiles.
• Ligand and Catalyst Development: Used in research to create novel picolinate-based ligands for metal catalysis and coordination chemistry applications.
• Material Science Research: Employed in the development of specialty chemicals and functional materials that require fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 6-Chloro-5-(Trifluoromethyl)Picolinate
CAS No.	1211518-35-2
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	Methyl 6-chloro-5-(trifluoromethyl)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 6-chloro-5-(trifluoromethyl)-, methyl ester; 6-Chloro-5-(trifluoromethyl)picolinic acid methyl ester; Methyl 6-chloro-5-trifluoromethylpicolinate; 6-Chloro-5-trifluoromethyl-picolinic acid methyl ester; Methyl 2-chloro-3-(trifluoromethyl)isonicotinate (isomer); Picolinate ester intermediate
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Chloro-5-(Trifluoromethyl)Picolinate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical parameters such as assay, impurity profile, and residual solvents. Our quality system is designed to meet the rigorous standards required for GMP and ISO-guided manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.