Description

2-Ethynyl-4-Nitropyridine CAS NO 1211515-78-4 is a high-value, multi-functional heterocyclic building block characterized by its reactive ethynyl and nitro functional groups. This compound is critical for advanced organic synthesis, enabling the rapid construction of complex molecular architectures through cross-coupling and cycloaddition reactions. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to develop new active ingredients for crop protection with potential novel modes of action.
• Material Science: Building block for creating conjugated polymers and organic electronic materials for OLEDs or sensors.
• Ligand Synthesis: Serves as a starting material for preparing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Click Chemistry: The ethynyl group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Academic & Contract Research: Essential reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Ethynyl-4-Nitropyridine
CAS No.	1211515-78-4
Molecular Formula	C7H4N2O2
Molecular Weight	148.12 g/mol
Synonyms	4-Nitro-2-ethynylpyridine; 2-Ethynyl-4-nitropyridine; Pyridine, 2-ethynyl-4-nitro-; 4-Nitro-2-ethynylpyridine; 2-(Ethynyl)-4-nitropyridine
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-4-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and relevant physical data.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its light-sensitive and easily oxidized nature, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.