Description

4-(4-Chloro-Phenylsulfanylmethyl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core functionalized with a chlorophenylthio-methyl group. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for neurological and psychiatric disorders.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a functionalized piperidine scaffold.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging its chlorophenyl moiety.
• Chemical Biology: Employed as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Utilized in university and institutional labs for methodological development and the study of sulfur-containing heterocycles.

Basic Information

Product Name	4-(4-Chloro-Phenylsulfanylmethyl)-Piperidine Hydrochloride
CAS No.	1211431-11-6
Molecular Formula	C12H17Cl2NS
Molecular Weight	278.24 g/mol
Synonyms	4-[(4-Chlorophenyl)thiomethyl]piperidine hydrochloride; 1-[(4-Chlorophenyl)thio]methyl-4-piperidine hydrochloride; 4-((4-Chlorophenylthio)methyl)piperidine HCl; Piperidine, 4-[(4-chlorophenyl)thio]methyl-, hydrochloride (1:1); 4-(4-Chloro-benzenesulfanylmethyl)-piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-Phenylsulfanylmethyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.