Description

Lgh447 is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is critical for the development of novel therapeutic agents, particularly in targeted oncology and kinase inhibitor research. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors for cancer therapy.
• Biochemical Research: Used as a reference standard and active probe in enzymatic and cellular assay development.
• Preclinical Development: Serves as a crucial material for pharmacokinetic, pharmacodynamic, and toxicology studies.
• Process Chemistry: Employed in route scouting and optimization for scalable Active Pharmaceutical Ingredient (API) manufacturing.
• Academic Research: Facilitates the study of specific biological pathways and target validation in university and institutional labs.

Basic Information

Product Name	Lgh447
CAS No.	1210416-52-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LGH447; LGH-447; UNII-8JQ5607E5S; 8JQ5607E5S; (S)-N-(5-((2-(Dimethylamino)ethyl)(methyl)amino)-2-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide; PIM447; PIM-447; PIM447 (LGH447); LGH 447
EINECS	Contact for details

Quality Control

Our Lgh447 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are supported by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.