Description

3-[[[3,5-Bis(Trifluoromethyl)Phenyl]Methyl]Amino]-4-[[(8α,9S)-6'-Methoxycinchonan-9-Yl]Amino]-3-Cyclobutene-1,2-Dione is a sophisticated, high-purity organic compound designed for advanced chemical synthesis and research. This molecule is of significant interest due to its complex structure, which incorporates a cinchona alkaloid derivative and a trifluoromethylated phenyl group, making it a valuable chiral building block or ligand in asymmetric catalysis. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Asymmetric Synthesis Catalyst: Acts as a chiral ligand or organocatalyst in enantioselective reactions for pharmaceutical intermediate production.
• Pharmaceutical Research Intermediate: Serves as a key building block in the synthesis of complex, biologically active molecules for drug discovery programs.
• Methodology Development: Used in academic and industrial research to develop new catalytic protocols and synthetic transformations.
• Fine Chemical Synthesis: Employed in the preparation of high-value specialty chemicals requiring precise stereochemical control.
• Ligand for Metal Complexation: Potential use in creating metal-organic complexes for catalysis or material science applications.

Basic Information

Product Name	3-[[[3,5-Bis(Trifluoromethyl)Phenyl]Methyl]Amino]-4-[[(8α,9S)-6'-Methoxycinchonan-9-Yl]Amino]-3-Cyclobutene-1,2-Dione
CAS No.	1210360-60-3
Molecular Formula	C₃₄H₂₈F₆N₄O₄
Molecular Weight	670.61 g/mol
Synonyms	3-(((3,5-Bis(trifluoromethyl)benzyl)amino)-4-(((8α,9S)-6'-methoxycinchonan-9-yl)amino)cyclobut-3-ene-1,2-dione; Cinchona Alkaloid-Derived Cyclobutenedione; (8α,9S)-9-((4-(((3,5-Bis(trifluoromethyl)benzyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-6'-methoxycinchonan; Chiral Cinchona Ligand; Asymmetric Catalyst Intermediate; 1210360-60-3; 3-[[[3,5-Bis(Trifluoromethyl)Phenyl]Methyl]Amino]-4-[[(8α,9S)-6'-Methoxycinchonan-9-Yl]Amino]-3-Cyclobutene-1,2-Dione
EINECS	Contact for details

Quality Control

Our production of this advanced chemical intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and relevant physicochemical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.