Description

Ertugliflozin CAS NO 1210344-57-2 is a high-purity, selective sodium-glucose cotransporter 2 (SGLT2) inhibitor active pharmaceutical ingredient (API). This compound is critical for the development and manufacturing of innovative antidiabetic medications. It is primarily required by pharmaceutical companies and research institutions engaged in metabolic disease therapeutics, formulation development, and clinical trial material production.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of SGLT2 inhibitor class antidiabetic drugs.
• Reference standard for analytical method development and validation in quality control laboratories.
• Key intermediate in advanced pharmaceutical research and new drug development projects.
• Raw material for the formulation of solid oral dosage forms such as tablets and capsules.
• Biochemical research tool for studying glucose reabsorption mechanisms in renal proximal tubules.
• Use in preclinical and clinical studies for evaluating pharmacokinetics and pharmacodynamics.

Basic Information

Item	Detail
Product Name	Ertugliflozin
CAS No.	1210344-57-2
Molecular Formula	C22H25ClO6
Molecular Weight	420.89 g/mol
Synonyms	(1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol; PF-04971729; Ertugliflozin L-pyroglutamic acid; Steglatro (Brand Name); MK-8835; (1S,2S,3S,4R,5S)-5-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
EINECS	Contact for details

Quality Control

Our Ertugliflozin is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with ICH guidelines and current Good Manufacturing Practice (cGMP) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider using desiccants and maintaining conditions under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.10%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.