Description

4-Bromo-2-Cyclopropoxypyridine is a high-value brominated pyridine derivative featuring a cyclopropoxy substituent, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	4-Bromo-2-Cyclopropoxypyridine
CAS No.	1209460-14-9
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	2-Cyclopropoxy-4-bromopyridine; 4-Bromo-2-(cyclopropyloxy)pyridine; Pyridine, 4-bromo-2-cyclopropoxy-; 4-Bromo-2-cyclopropyloxypyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Cyclopropoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.