Description

6-Bromopyrazine-2-Carboxamide is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the pyrazine-carboxamide pharmacophore.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazine core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the synthesis of organic electronic materials and functional polymers where the bromine moiety allows for further cross-coupling reactions.
• Chemical Biology Probes: Utilized to create tool compounds and molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	6-Bromopyrazine-2-Carboxamide
CAS No.	1209459-76-6
Molecular Formula	C5H4BrN3O
Molecular Weight	202.01 g/mol
Synonyms	6-Bromo-2-pyrazinecarboxamide; 6-Bromopyrazinecarboxamide; 2-Pyrazinecarboxamide, 6-bromo-; 6-Bromo-pyrazine-2-carboxylic acid amide; 6-Bromopyrazine-2-carboxylic acid amide; 1209459-76-6; 6-Bromopyrazinecarboxylic acid amide
EINECS	Contact for details

Quality Control

Our 6-Bromopyrazine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.