Description

2-Bromo-6-Fluoropyrazine is a high-purity halogenated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine and bromine functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and pesticides, leveraging the biological activity of fluorinated pyrazines.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	2-Bromo-6-Fluoropyrazine
CAS No.	1209458-12-7
Molecular Formula	C4H2BrFN2
Molecular Weight	176.97 g/mol
Synonyms	6-Fluoro-2-bromopyrazine; 2-Bromo-6-fluoropyrazine; Fluoropyrazine, bromo-; Pyrazine, 2-bromo-6-fluoro-; Bromofluoropyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoropyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.