Description

2-Chloro-6-Cyclopropylpyrazine is a high-purity, heterocyclic organic compound featuring a pyrazine core substituted with chloro and cyclopropyl groups. This specific molecular architecture makes it a versatile and critical building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a crucial precursor in the design and synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrazine moiety.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or conductive polymers.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	2-Chloro-6-Cyclopropylpyrazine
CAS No.	1209457-99-7
Molecular Formula	C7H7ClN2
Molecular Weight	154.60 g/mol
Synonyms	2-Chloro-6-cyclopropylpyrazine; 6-Chloro-3-cyclopropylpyrazine; Pyrazine, 2-chloro-6-cyclopropyl-; 2-Chloro-6-cyclopropyl-1,4-diazine; 2-Chloro-6-cyclopropylpyrazine (CAS 1209457-99-7)
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Cyclopropylpyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Standard quality control includes chromatographic purity analysis (HPLC/GC) and structural confirmation (NMR, MS). A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.