Description

5-Bromo-3-Ethynylpyrazin-2-Amine is a high-purity, multi-functional heterocyclic building block featuring both bromo and ethynyl substituents on a pyrazine core. This compound is of significant value in modern synthetic chemistry, enabling efficient cross-coupling reactions and serving as a versatile scaffold for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Research: Used to build novel heterocyclic scaffolds for the development of new herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of chemical tools for biological studies.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	5-Bromo-3-Ethynylpyrazin-2-Amine
CAS No.	1209289-08-6
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-3-ethynyl-2-pyrazinamine; 2-Amino-5-bromo-3-ethynylpyrazine; 3-Ethynyl-5-bromopyrazin-2-amine; 1209289-08-6; 5-Bromo-3-ethynylpyrazin-2-ylamine; 5-Bromo-3-ethynyl-2-aminopyrazine; 2-Pyrazinamine, 5-bromo-3-ethynyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Ethynylpyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.