Description

2-Methyl-2-(Pyrazin-2-Yl)Propanoic Acid is a high-purity, synthetically valuable organic building block characterized by its unique sterically hindered carboxylic acid group adjacent to a pyrazine heterocycle. This molecular architecture makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where it is prized for introducing specific steric and electronic properties. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrazine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands in organometallic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional organic molecules for electronic materials or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.

Basic Information

Product Name	2-Methyl-2-(Pyrazin-2-Yl)Propanoic Acid
CAS No.	1209049-55-7
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	2-(2-Pyrazinyl)-2-methylpropanoic acid; α,α-Dimethyl-2-pyrazineacetic acid; 2-Methyl-2-pyrazin-2-ylpropionic acid; 2-Pyrazineacetic acid, α,α-dimethyl-; 2-(Pyrazin-2-yl)-2-methylpropanoic acid; 1209049-55-7; Tert-butylpyrazine-2-carboxylic acid (related structure)
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(Pyrazin-2-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory/industrial practices for chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.