Description

1-[5-Bromo-3-(Trifluoromethyl)-2-Pyridyl]-4-Methyl-Piperazine is a high-purity, advanced pharmaceutical intermediate and building block of significant commercial importance. This compound is valued for its unique molecular structure, which incorporates both bromo and trifluoromethyl substituents on a pyridine ring, enabling precise chemical modifications in complex syntheses. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine-piperazine scaffold.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of targeted molecular libraries for high-throughput screening.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring brominated, fluorinated heterocycles.

Basic Information

Product Name	1-[5-Bromo-3-(Trifluoromethyl)-2-Pyridyl]-4-Methyl-Piperazine
CAS No.	1208081-84-8
Molecular Formula	C11H11BrF3N3
Molecular Weight	322.13 g/mol
Synonyms	4-Methyl-1-[5-bromo-3-(trifluoromethyl)pyridin-2-yl]piperazine; 1-(5-Bromo-3-(trifluoromethyl)pyridin-2-yl)-4-methylpiperazine; 2-(4-Methylpiperazin-1-yl)-5-bromo-3-(trifluoromethyl)pyridine; 5-Bromo-3-(trifluoromethyl)-2-(4-methyl-1-piperazinyl)pyridine; 5-Bromo-3-trifluoromethyl-2-(4-methylpiperazin-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our production of 1-[5-Bromo-3-(Trifluoromethyl)-2-Pyridyl]-4-Methyl-Piperazine adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.