Description

6'-Chloro-4'-Trifluoromethyl-3,4,5,6-Tetrahydro-2 H-[1,2']Bipyridinyl-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for constructing molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique bipyridinyl scaffold.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation herbicides and pesticides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6'-Chloro-4'-Trifluoromethyl-3,4,5,6-Tetrahydro-2 H-[1,2']Bipyridinyl-4-Carboxylic Acid
CAS No.	1208081-19-9
Molecular Formula	C13H12ClF3N2O2
Molecular Weight	320.70 g/mol
Synonyms	6'-Chloro-4'-(trifluoromethyl)-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine]-4-carboxylic acid; 2H-[1,2'-Bipyridine]-4-carboxylic acid, 6'-chloro-4'-(trifluoromethyl)-3,4,5,6-tetrahydro-; 6'-Chloro-4'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid; 1208081-19-9; CAS 1208081-19-9
EINECS	Contact for details

Quality Control

Our 6'-Chloro-4'-Trifluoromethyl-3,4,5,6-Tetrahydro-2 H-[1,2']Bipyridinyl-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.