Description

2,5-Difluoropyrazine is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in the strategic introduction of fluorine atoms and the pyrazine core, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where it serves as a key precursor for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in cross-coupling and other metal-mediated reactions.
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic and fluorine chemistry.
• Fluorine-18 Radiochemistry: Potential use as a precursor or model compound in the development of Positron Emission Tomography (PET) imaging agents.

Basic Information

Product Name	2,5-Difluoropyrazine
CAS No.	1207861-11-7
Molecular Formula	C4H2F2N2
Molecular Weight	116.07 g/mol
Synonyms	2,5-Difluoropyrazine; Pyrazine, 2,5-difluoro-; 2,5-Difluoro-1,4-diazine; 2,5-Difluoropyrazine (CAS 1207861-11-7); 2,5-Difluoro-pyrazine; 1,4-Diazine, 2,5-difluoro-; Difluoropyrazine
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoropyrazine is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed using techniques including GC, HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.