Description

2-Bromo-Pyrrolo[2,3-B]Pyrazine-5-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its reactive bromine and ester functional groups.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	2-Bromo-Pyrrolo[2,3-B]Pyrazine-5-Carboxylic Acid tert-Butyl Ester
CAS No.	1207625-13-5
Molecular Formula	C11H12BrN3O2
Molecular Weight	298.14 g/mol
Synonyms	tert-Butyl 2-bromo-7H-pyrrolo[2,3-b]pyrazine-5-carboxylate; 2-Bromo-7H-pyrrolo[2,3-b]pyrazine-5-carboxylic acid 1,1-dimethylethyl ester; 2-Bromo-pyrrolo[2,3-b]pyrazine-5-carboxylic acid t-butyl ester; 2-Bromo-5-(tert-butoxycarbonyl)-7H-pyrrolo[2,3-b]pyrazine; 1207625-13-5; Pyrrolo[2,3-b]pyrazine, 2-bromo-5-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Bromo-Pyrrolo[2,3-B]Pyrazine-5-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Individual impurity ≤1.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.