Description

cis-1-n-Boc-3-Methyl-Isonipecoticacid CAS NO 1207267-93-3 is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block and intermediate in the development of complex pharmaceutical molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Peptidomimetics & Drug Discovery: Used in medicinal chemistry for constructing constrained peptide analogs and small molecule libraries to explore new therapeutic targets.
• Agrochemical Synthesis: Serves as a building block for creating novel, optically active pesticides and herbicides with improved efficacy.
• Catalyst & Ligand Development: Employed in the preparation of chiral catalysts and ligands for asymmetric synthesis applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring high stereochemical purity and a protected carboxylic acid functionality.

Basic Information

Product Name	cis-1-n-Boc-3-Methyl-Isonipecoticacid
CAS No.	1207267-93-3
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	1-Boc-3-methylpiperidine-4-carboxylic acid (cis); cis-1-(tert-Butoxycarbonyl)-3-methylpiperidine-4-carboxylic acid; (3R,4S)-1-Boc-3-methylpiperidine-4-carboxylic acid; (3S,4R)-1-Boc-3-methylpiperidine-4-carboxylic acid; cis-1-tert-Butyl 4-carboxy-3-methylpiperidine-1,4-dicarboxylate; 3-Methyl-1-Boc-isonipecotic acid (cis); 1-N-Boc-3-methylisonipecotic acid (cis)
EINECS	Contact for details

Quality Control

Our cis-1-n-Boc-3-Methyl-Isonipecoticacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.