Description

2-Chloro-3-(trifluoromethoxy)pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, combining a halogenated pyridine core with a trifluoromethoxy substituent, makes it an essential intermediate for introducing specific physicochemical properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced electronic materials for specialized applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-3-(trifluoromethoxy)pyridine
CAS No.	1206980-39-3
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	2-Chloro-3-(trifluoromethoxy)pyridine; 3-Trifluoromethoxy-2-chloropyridine; 2-Chloro-3-trifluoromethoxypyridine; Pyridine, 2-chloro-3-(trifluoromethoxy)-; 1206980-39-3
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(trifluoromethoxy)pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.